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Antiviral Effects of Clinically-Relevant Interferon-α and Ribavirin Regimens against Dengue Virus in the Hollow Fiber Infection Model (HFIM)

Dengue virus (DENV) is the most prevalent mosquito-borne viral illness in humans. Currently, there are no therapeutic agents available to prevent or treat DENV infections. Our objective was to fill this unmet medical need by evaluating the antiviral activity of interferon-α (IFN) and ribavirin (RBV)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Viruses
Hauptverfasser: Pires de Mello, Camilly P., Drusano, George L., Rodriquez, Jaime L., Kaushik, Ajeet, Brown, Ashley N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024321/
https://ncbi.nlm.nih.gov/pubmed/29890736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10060317
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