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Antiviral Effects of Clinically-Relevant Interferon-α and Ribavirin Regimens against Dengue Virus in the Hollow Fiber Infection Model (HFIM)

Dengue virus (DENV) is the most prevalent mosquito-borne viral illness in humans. Currently, there are no therapeutic agents available to prevent or treat DENV infections. Our objective was to fill this unmet medical need by evaluating the antiviral activity of interferon-α (IFN) and ribavirin (RBV)...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Pires de Mello, Camilly P., Drusano, George L., Rodriquez, Jaime L., Kaushik, Ajeet, Brown, Ashley N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024321/
https://ncbi.nlm.nih.gov/pubmed/29890736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10060317
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