Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were...

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Bibliografski detalji
Izdano u:mBio
Glavni autori: Brown, Ashley N., Drusano, George L., Adams, Jonathan R., Rodriquez, Jaime L., Jambunathan, Kalyani, Baluya, Dodge L., Brown, David L., Kwara, Awewura, Mirsalis, Jon C., Hafner, Richard, Louie, Arnold
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631805/
https://ncbi.nlm.nih.gov/pubmed/26530386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01741-15
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