Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Brown, Ashley N., Drusano, George L., Adams, Jonathan R., Rodriquez, Jaime L., Jambunathan, Kalyani, Baluya, Dodge L., Brown, David L., Kwara, Awewura, Mirsalis, Jon C., Hafner, Richard, Louie, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631805/
https://ncbi.nlm.nih.gov/pubmed/26530386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01741-15
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