Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were...

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Enregistré dans:
Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Brown, Ashley N., Drusano, George L., Adams, Jonathan R., Rodriquez, Jaime L., Jambunathan, Kalyani, Baluya, Dodge L., Brown, David L., Kwara, Awewura, Mirsalis, Jon C., Hafner, Richard, Louie, Arnold
Format: Artigo
Langue:Inglês
Publié: American Society of Microbiology 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631805/
https://ncbi.nlm.nih.gov/pubmed/26530386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01741-15
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