Interaction of Drug- and Granulocyte-Mediated Killing of Pseudomonas aeruginosa in a Murine Pneumonia Model

Background. Killing of bacterial pathogens by granulocytes is a saturable process, as previously demonstrated. There is virtually no quantitative information about how granulocytes interact with antimicrobial chemotherapy to kill bacterial cells. Methods. We performed a dose-ranging study with the a...

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Vydáno v:J Infect Dis
Hlavní autoři: Drusano, George Louis, Liu, Weiguo, Fikes, Steven, Cirz, Ryan, Robbins, Nichole, Kurhanewicz, Stephanie, Rodriquez, Jaime, Brown, David, Baluya, Dodge, Louie, Arnold
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271070/
https://ncbi.nlm.nih.gov/pubmed/24760199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu237
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