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Impact of Meropenem in Combination with Tobramycin in a Murine Model of Pseudomonas aeruginosa Pneumonia

Pseudomonas aeruginosa pneumonia remains a difficult therapeutic problem. Optimal doses and modes of administration of single agents often do not result in acceptable outcomes. Further, emergence of resistance occurs frequently in this setting with single-agent chemotherapy. The purpose of these exp...

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Bibliographic Details
Main Authors: Louie, Arnold, Liu, Weiguo, Fikes, Steven, Brown, David, Drusano, G. L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716130/
https://ncbi.nlm.nih.gov/pubmed/23571540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02624-12
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