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Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

The base excision repair protein, MUTYH, functionally interacts with the DNA mismatch repair (MMR) system. As genetic testing moves from testing one gene at a time, to gene panel and whole exome next generation sequencing approaches, understanding the risk associated with co-existence of germline mu...

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Bibliografische gegevens
Gepubliceerd in:Fam Cancer
Hoofdauteurs: Win, Aung Ko, Reece, Jeanette C., Buchanan, Daniel D., Clendenning, Mark, Young, Joanne P., Cleary, Sean P., Kim, Hyeja, Cotterchio, Michelle, Dowty, James G., MacInnis, Robert J., Tucker, Katherine M., Winship, Ingrid M., Macrae, Finlay A., Burnett, Terrilea, Le Marchand, Loïc, Casey, Graham, Haile, Robert W., Newcomb, Polly A., Thibodeau, Stephen N., Lindor, Noralane M., Hopper, John L., Gallinger, Steven, Jenkins, Mark A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631636/
https://ncbi.nlm.nih.gov/pubmed/26202870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9824-x
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