Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

The base excision repair protein, MUTYH, functionally interacts with the DNA mismatch repair (MMR) system. As genetic testing moves from testing one gene at a time, to gene panel and whole exome next generation sequencing approaches, understanding the risk associated with co-existence of germline mu...

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Опубликовано в: :Fam Cancer
Главные авторы: Win, Aung Ko, Reece, Jeanette C., Buchanan, Daniel D., Clendenning, Mark, Young, Joanne P., Cleary, Sean P., Kim, Hyeja, Cotterchio, Michelle, Dowty, James G., MacInnis, Robert J., Tucker, Katherine M., Winship, Ingrid M., Macrae, Finlay A., Burnett, Terrilea, Le Marchand, Loïc, Casey, Graham, Haile, Robert W., Newcomb, Polly A., Thibodeau, Stephen N., Lindor, Noralane M., Hopper, John L., Gallinger, Steven, Jenkins, Mark A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631636/
https://ncbi.nlm.nih.gov/pubmed/26202870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9824-x
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