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The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signaling
The Spindle Assembly Checkpoint (SAC) is a unique signaling mechanism that responds to the state of attachment of the kinetochore to spindle microtubules. SAC signaling is activated by unattached kinetochores, and it is silenced after these kinetochores form end-on microtubule attachments. Although...
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| Publié dans: | Nat Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4630029/ https://ncbi.nlm.nih.gov/pubmed/26053220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3179 |
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