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Kinetochore stretching inactivates the spindle assembly checkpoint

The spindle assembly checkpoint (SAC) monitors the attachment of microtubules to the kinetochore and inhibits anaphase when microtubule binding is incomplete. The SAC might also respond to tension; however, how cells can sense tension and whether its detection is important to satisfy the SAC remain...

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Detalles Bibliográficos
Main Authors: Uchida, Kazuhiko S.K., Takagaki, Kentaro, Kumada, Kazuki, Hirayama, Youko, Noda, Tetsuo, Hirota, Toru
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646554/
https://ncbi.nlm.nih.gov/pubmed/19188492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811028
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