Kinetochore stretching inactivates the spindle assembly checkpoint

The spindle assembly checkpoint (SAC) monitors the attachment of microtubules to the kinetochore and inhibits anaphase when microtubule binding is incomplete. The SAC might also respond to tension; however, how cells can sense tension and whether its detection is important to satisfy the SAC remain...

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Bibliographic Details
Main Authors: Uchida, Kazuhiko S.K., Takagaki, Kentaro, Kumada, Kazuki, Hirayama, Youko, Noda, Tetsuo, Hirota, Toru
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646554/
https://ncbi.nlm.nih.gov/pubmed/19188492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811028
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