Kinetochore stretching inactivates the spindle assembly checkpoint

The spindle assembly checkpoint (SAC) monitors the attachment of microtubules to the kinetochore and inhibits anaphase when microtubule binding is incomplete. The SAC might also respond to tension; however, how cells can sense tension and whether its detection is important to satisfy the SAC remain...

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Bibliografske podrobnosti
Main Authors: Uchida, Kazuhiko S.K., Takagaki, Kentaro, Kumada, Kazuki, Hirayama, Youko, Noda, Tetsuo, Hirota, Toru
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646554/
https://ncbi.nlm.nih.gov/pubmed/19188492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811028
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