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Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore

Recruitment of spindle assembly checkpoint (SAC) proteins by an unattached kinetochore leads to SAC activation. This recruitment is licensed by the Mps1 kinase, which phosphorylates the kinetochore protein Spc105 at one or more of its six MELT repeats. Spc105 then recruits the Bub3-Bub1 and Mad1-Mad...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Aravamudhan, Pavithra, Chen, Renjie, Roy, Babhrubahan, Sim, Janice, Joglekar, Ajit P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221577/
https://ncbi.nlm.nih.gov/pubmed/27170178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-01-0007
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