NF-κB and STAT3 Transcription Factor Signatures Differentiate HPV-positive and HPV-negative Head and Neck Squamous Cell Carcinoma

Using high-throughput analyses and the TRANSFAC database, we characterized TF signatures of head and neck squamous cell carcinoma (HNSCC) subgroups by inferential analysis of target gene expression, correcting for the effects of DNA methylation and copy number. Using this discovery pipeline, we dete...

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Publicado en:Int J Cancer
Autores principales: Gaykalova, Daria A., Manola, Judith B., Ozawa, Hiroyuki, Zizkova, Veronika, Morton, Kathryn, Bishop, Justin A., Sharma, Rajni, Zhang, Chi, Michailidi, Christina, Considine, Michael, Tan, Marietta, Fertig, Elana J., Hennessey, Patrick T., Ahn, Julie, Koch, Wayne M., Westra, William H., Khan, Zubair, Chung, Christine H., Ochs, Michael F., Califano, Joseph A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629062/
https://ncbi.nlm.nih.gov/pubmed/25857630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29558
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