NF-κB and STAT3 Transcription Factor Signatures Differentiate HPV-positive and HPV-negative Head and Neck Squamous Cell Carcinoma

Using high-throughput analyses and the TRANSFAC database, we characterized TF signatures of head and neck squamous cell carcinoma (HNSCC) subgroups by inferential analysis of target gene expression, correcting for the effects of DNA methylation and copy number. Using this discovery pipeline, we dete...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Gaykalova, Daria A., Manola, Judith B., Ozawa, Hiroyuki, Zizkova, Veronika, Morton, Kathryn, Bishop, Justin A., Sharma, Rajni, Zhang, Chi, Michailidi, Christina, Considine, Michael, Tan, Marietta, Fertig, Elana J., Hennessey, Patrick T., Ahn, Julie, Koch, Wayne M., Westra, William H., Khan, Zubair, Chung, Christine H., Ochs, Michael F., Califano, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629062/
https://ncbi.nlm.nih.gov/pubmed/25857630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29558
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