O-GlcNAcase overexpression reverses coronary endothelial cell dysfunction in type 1 diabetic mice

Cardiovascular disease is the primary cause of morbidity and mortality in diabetes, and endothelial dysfunction is commonly seen in these patients. Increased O-linked N-acetylglucosamine (O-GlcNAc) protein modification is one of the central pathogenic features of diabetes. Modification of proteins b...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Makino, Ayako, Dai, Anzhi, Han, Ying, Youssef, Katia D., Wang, Weihua, Donthamsetty, Reshma, Scott, Brian T., Wang, Hong, Dillmann, Wolfgang H.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628934/
https://ncbi.nlm.nih.gov/pubmed/26269457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00069.2015
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