Načítá se...
Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells
BACKGROUND: Mutations in the gene encoding Ubiquilin-2 (UBQLN2) are linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). UBQLN2 plays a central role in ubiquitin proteasome system (UPS) and UBQLN2 mutants can form cytoplasmic aggregates in vitro and in vivo. RESULTS: Here...
Uloženo v:
| Vydáno v: | Mol Brain |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2015
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628361/ https://ncbi.nlm.nih.gov/pubmed/26521126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0162-6 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|