DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation

A common pathological hallmark of several neurodegenerative diseases, including amyotrophic lateral sclerosis, is cytoplasmic mislocalization and aggregation of nuclear RNA-binding protein TDP-43. Perry disease, which displays inherited atypical parkinsonism, is a type of TDP-43 proteinopathy. The c...

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Publicado no:Int J Mol Sci
Main Authors: Deshimaru, Manami, Kinoshita-Kawada, Mariko, Kubota, Kaori, Watanabe, Takuya, Tanaka, Yasuyoshi, Hirano, Saito, Ishidate, Fumiyoshi, Hiramoto, Masaki, Ishikawa, Mitsuru, Uehara, Yoshinari, Okano, Hideyuki, Hirose, Shinichi, Fujioka, Shinsuke, Iwasaki, Katsunori, Yuasa-Kawada, Junichi, Mishima, Takayasu, Tsuboi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070438/
https://ncbi.nlm.nih.gov/pubmed/33924373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083985
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