Genetic and Morphological Features of Human iPSC-Derived Neurons with Chromosome 15q11.2 (BP1-BP2) Deletions

BACKGROUND: Copy number variation on chromosome 15q11.2 (BP1-BP2) causes a deletion of CYFIP1, NIPA1, NIPA2 and TUBGCP5. Furthermore, it also affects brain structure and elevates the risk for several neurodevelopmental disorders that are associated with dendritic spine abnormalities. In rodents, alt...

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Vydáno v:Mol Neuropsychiatry
Hlavní autoři: Das, Dhanjit K., Tapias, Victor, D'Aiuto, Leonardo, Chowdari, Kodavali V., Francis, Lily, Zhi, Yun, Ghosh, Ayantika, Surti, Urvashi, Tischfield, Jay, Sheldon, Michael, Moore, Jennifer C., Fish, Ken, Nimgaonkar, Vishwajit L.
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2015
Témata:
Preliminary Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627696/
https://ncbi.nlm.nih.gov/pubmed/26528485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000430916
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