Persistent Infection by HSV-1 Is Associated With Changes in Functional Architecture of iPSC-Derived Neurons and Brain Activation Patterns Underlying Working Memory Performance

BACKGROUND: Herpes simplex virus, type 1 (HSV-1) commonly produces lytic mucosal lesions. It invariably initiates latent infection in sensory ganglia enabling persistent, lifelong infection. Acute HSV-1 encephalitis is rare and definitive evidence of latent infection in the brain is lacking. However...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Schizophr Bull
Main Authors: D’Aiuto, Leonardo, Prasad, Konasale M., Upton, Catherine H., Viggiano, Luigi, Milosevic, Jadranka, Raimondi, Giorgio, McClain, Lora, Chowdari, Kodavali, Tischfield, Jay, Sheldon, Michael, Moore, Jennifer C., Yolken, Robert H., Kinchington, Paul R., Nimgaonkar, Vishwajit L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266288/
https://ncbi.nlm.nih.gov/pubmed/24622295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbu032
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