Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients–a pilot study

A recent report suggested Complement 4 (C4A) gene copy numbers (GCN) as risk factors for schizophrenia. Rodent model showed association of C4 with synaptic pruning suggesting its pathophysiological significance (Sekar, A. et al. (2016)). We, therefore, predicted that C4A GCN would be positively corr...

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Foilsithe in:Transl Psychiatry
Main Authors: Prasad, Konasale M., Chowdari, Kodavali V., D’Aiuto, Leonardo A., Iyengar, Satish, Stanley, Jeffrey A., Nimgaonkar, Vishwajit L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053402/
https://ncbi.nlm.nih.gov/pubmed/30026462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0181-z
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