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Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients–a pilot study

A recent report suggested Complement 4 (C4A) gene copy numbers (GCN) as risk factors for schizophrenia. Rodent model showed association of C4 with synaptic pruning suggesting its pathophysiological significance (Sekar, A. et al. (2016)). We, therefore, predicted that C4A GCN would be positively corr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Transl Psychiatry
Main Authors: Prasad, Konasale M., Chowdari, Kodavali V., D’Aiuto, Leonardo A., Iyengar, Satish, Stanley, Jeffrey A., Nimgaonkar, Vishwajit L.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053402/
https://ncbi.nlm.nih.gov/pubmed/30026462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0181-z
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