Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1β secretion in a model of human THP-1 monocytes

Type III secretion system (T3SS) in Pseudomonas aeruginosa is associated with poor clinical outcome in acute infections. T3SS allows for injection of bacterial exotoxins (e.g. ExoU or ExoS) into the host cell, causing cytotoxicity. It also activates the cytosolic NLRC4 inflammasome, activating caspa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pathog Dis
Egile Nagusiak: Anantharajah, Ahalieyah, Buyck, Julien M., Faure, Emmanuel, Glupczynski, Youri, Rodriguez-Villalobos, Hector, De Vos, Daniel, Pirnay, Jean-Paul, Bilocq, Florence, Guery, Benoît, Tulkens, Paul M., Mingeot-Leclercq, Marie-Paule, Van Bambeke, Françoise
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Short Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626600/
https://ncbi.nlm.nih.gov/pubmed/26203053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv049
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