Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis

Iron-mediated oxidative stress is implicated in the pathogenesis of renal ischemia–reperfusion injury. Hepcidin is an endogenous acute phase hepatic hormone that prevents iron export from cells by inducing degradation of the only known iron export protein, ferroportin. In this study, we used a mouse...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Scindia, Yogesh, Dey, Paromita, Thirunagari, Abhinav, Liping, Huang, Rosin, Diane L., Floris, Matteo, Okusa, Mark D., Swaminathan, Sundararaman
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625680/
https://ncbi.nlm.nih.gov/pubmed/25788528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101037
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