Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis

Iron-mediated oxidative stress is implicated in the pathogenesis of renal ischemia–reperfusion injury. Hepcidin is an endogenous acute phase hepatic hormone that prevents iron export from cells by inducing degradation of the only known iron export protein, ferroportin. In this study, we used a mouse...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Scindia, Yogesh, Dey, Paromita, Thirunagari, Abhinav, Liping, Huang, Rosin, Diane L., Floris, Matteo, Okusa, Mark D., Swaminathan, Sundararaman
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2015
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625680/
https://ncbi.nlm.nih.gov/pubmed/25788528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101037
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