Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury

Background: Acute kidney injury (AKI) portends worse prognosis following sepsis, with limited available interventions. Host iron acquisition by pathogens and systemic inflammatory response are key events in the pathogenesis of sepsis. In sepsis, hepcidin induces iron sequestration to limit iron avai...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Scindia, Yogesh, Wlazlo, Ewa, Leeds, Joseph, Loi, Valentina, Ledesma, Jonathan, Cechova, Sylvia, Ghias, Elizabeth, Swaminathan, Sundararaman
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563000/
https://ncbi.nlm.nih.gov/pubmed/31244655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00615
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