Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury

Background: Acute kidney injury (AKI) portends worse prognosis following sepsis, with limited available interventions. Host iron acquisition by pathogens and systemic inflammatory response are key events in the pathogenesis of sepsis. In sepsis, hepcidin induces iron sequestration to limit iron avai...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Scindia, Yogesh, Wlazlo, Ewa, Leeds, Joseph, Loi, Valentina, Ledesma, Jonathan, Cechova, Sylvia, Ghias, Elizabeth, Swaminathan, Sundararaman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563000/
https://ncbi.nlm.nih.gov/pubmed/31244655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00615
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