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MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP Dissociation Inhibitor alpha from the GDI/CHM family of RAB GTPase effectors

Photoreceptor outer segments (OS) in the vertebrate retina undergo a process of continual renewal involving shedding of disc membranes that are cleared by phagocytic uptake into the retinal pigment epithelium (RPE). In dystrophic Royal College of Surgeons (RCS) rats, OS phagocytosis is blocked by a...

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Bibliografische gegevens
Gepubliceerd in:Exp Eye Res
Hoofdauteurs: Shelby, Shameka J., Feathers, Kecia L., Ganios, Anna M., Jia, Lin, Miller, Jason M., Thompson, Debra A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624558/
https://ncbi.nlm.nih.gov/pubmed/26283020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.08.006
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