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MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP Dissociation Inhibitor alpha from the GDI/CHM family of RAB GTPase effectors

Photoreceptor outer segments (OS) in the vertebrate retina undergo a process of continual renewal involving shedding of disc membranes that are cleared by phagocytic uptake into the retinal pigment epithelium (RPE). In dystrophic Royal College of Surgeons (RCS) rats, OS phagocytosis is blocked by a...

詳細記述

保存先:
書誌詳細
出版年:Exp Eye Res
主要な著者: Shelby, Shameka J., Feathers, Kecia L., Ganios, Anna M., Jia, Lin, Miller, Jason M., Thompson, Debra A.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624558/
https://ncbi.nlm.nih.gov/pubmed/26283020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.08.006
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