MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP Dissociation Inhibitor alpha from the GDI/CHM family of RAB GTPase effectors

Photoreceptor outer segments (OS) in the vertebrate retina undergo a process of continual renewal involving shedding of disc membranes that are cleared by phagocytic uptake into the retinal pigment epithelium (RPE). In dystrophic Royal College of Surgeons (RCS) rats, OS phagocytosis is blocked by a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Eye Res
Auteurs principaux: Shelby, Shameka J., Feathers, Kecia L., Ganios, Anna M., Jia, Lin, Miller, Jason M., Thompson, Debra A.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624558/
https://ncbi.nlm.nih.gov/pubmed/26283020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.08.006
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