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Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI.

Prenylated Rab GTPases occur in the cytosol in their GDP-bound conformations bound to a cytosolic protein termed GDP-dissociation inhibitor (GDI). Rab-GDI complexes represent a pool of active, recycling Rab proteins that can deliver Rabs to specific and distinct membrane-bound compartments. Rab deli...

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Hlavní autoři: Dirac-Svejstrup, A B, Sumizawa, T, Pfeffer, S R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169650/
https://ncbi.nlm.nih.gov/pubmed/9034329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.3.465
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