A carregar...
The General Base in the Thymidylate Synthase Catalyzed Proton Abstraction
The enzyme thymidylate synthase (TSase), an important chemotherapeutic drug target, catalyzes the formation of 2′-deoxythymidine-5′-monophosphate (dTMP), a precursor of one of the DNA building blocks. TSase catalyzes a multi-step mechanism that includes the abstraction of a proton from the C5 of the...
Na minha lista:
| Publicado no: | Phys Chem Chem Phys |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624062/ https://ncbi.nlm.nih.gov/pubmed/25912171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cp01246e |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|