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Bacterial versus human thymidylate synthase: Kinetics and functionality

Thymidylate Synthase (TSase) is a highly conserved enzyme that catalyzes the production of the DNA building block thymidylate. Structurally, functionally and mechanistically, bacterial and mammalian TSases share remarkable similarities. Because of this closeness, bacterial enzymes have long been use...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Islam, Zahidul, Gurevic, Ilya, Strutzenberg, Timothy S., Ghosh, Ananda K., Iqbal, Tasnia, Kohen, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929524/
https://ncbi.nlm.nih.gov/pubmed/29715278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196506
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