MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin

It has been reported that persistent or excessive autophagy promotes cancer cell death during chemotherapy, either by enhancing the induction of apoptosis or mediating autophagic cell death. Here, we show that miR-15a and miR-16 are potent inducers of autophagy. Rictor, a component of mTORC2 complex...

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Publicat a:Cancer Biol Ther
Autors principals: Huang, Nunu, Wu, Jiangbin, Qiu, Wei, Lyu, Qing, He, Jie, Xie, Weidong, Xu, Naihan, Zhang, Yaou
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622988/
https://ncbi.nlm.nih.gov/pubmed/25945419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040963
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