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Conservation of miR-15a/16-1 and miR-15b/16-2 clusters

MiR-15a/16-1 and miR-15b/16-2 clusters have been shown to play very important roles in regulating cell proliferation and apoptosis by targeting cell cycle proteins and the antiapoptotic Bcl-2 gene. However, the physiological implications of those two clusters are largely elusive. By aligning the pri...

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Detalhes bibliográficos
Main Authors: Yue, Junming, Tigyi, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820079/
https://ncbi.nlm.nih.gov/pubmed/20013340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9240-3
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