miR-15b/16-2 deletion promotes B-cell malignancies

The central role of the microRNA (miR) 15a/16-1 cluster in B-cell oncogenesis has been extensively demonstrated, with over two-thirds of B-cell chronic lymphocytic leukemia characterized by the deletion of the miR-15a/16-1 locus at 13q14. Despite the well-established understanding of the molecular m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lovat, Francesca, Fassan, Matteo, Gasparini, Pierluigi, Rizzotto, Lara, Cascione, Luciano, Pizzi, Marco, Vicentini, Caterina, Balatti, Veronica, Palmieri, Dario, Costinean, Stefan, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577143/
https://ncbi.nlm.nih.gov/pubmed/26324892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514954112
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