miR-15 and miR-16 induce apoptosis by targeting BCL2

Chronic lymphocytic leukemia (CLL) is the most common human leukemia and is characterized by predominantly nondividing malignant B cells overexpressing the antiapoptotic B cell lymphoma 2 (Bcl2) protein. miR-15a and miR-16-1 are deleted or down-regulated in the majority of CLLs. Here, we demonstrate...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Cimmino, Amelia, Calin, George Adrian, Fabbri, Muller, Iorio, Marilena V., Ferracin, Manuela, Shimizu, Masayoshi, Wojcik, Sylwia E., Aqeilan, Rami I., Zupo, Simona, Dono, Mariella, Rassenti, Laura, Alder, Hansjuerg, Volinia, Stefano, Liu, Chang-gong, Kipps, Thomas J., Negrini, Massimo, Croce, Carlo M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236577/
https://ncbi.nlm.nih.gov/pubmed/16166262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506654102
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars