MiR-15a and miR-16-1 cluster functions in human leukemia

MicroRNAs (miRNAs) are short noncoding RNAs regulating gene expression that play roles in human diseases, including cancer. Each miRNA is predicted to regulate hundreds of transcripts, but only few have experimental validation. In chronic lymphocytic leukemia (CLL), the most common adult human leuke...

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Bibliographic Details
Main Authors: Calin, George A., Cimmino, Amelia, Fabbri, Muller, Ferracin, Manuela, Wojcik, Sylwia E., Shimizu, Masayoshi, Taccioli, Cristian, Zanesi, Nicola, Garzon, Ramiro, Aqeilan, Rami I., Alder, Hansjuerg, Volinia, Stefano, Rassenti, Laura, Liu, Xiuping, Liu, Chang-gong, Kipps, Thomas J., Negrini, Massimo, Croce, Carlo M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278188/
https://ncbi.nlm.nih.gov/pubmed/18362358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800121105
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