MiR-15a and miR-16-1 cluster functions in human leukemia

MicroRNAs (miRNAs) are short noncoding RNAs regulating gene expression that play roles in human diseases, including cancer. Each miRNA is predicted to regulate hundreds of transcripts, but only few have experimental validation. In chronic lymphocytic leukemia (CLL), the most common adult human leuke...

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Hauptverfasser: Calin, George A., Cimmino, Amelia, Fabbri, Muller, Ferracin, Manuela, Wojcik, Sylwia E., Shimizu, Masayoshi, Taccioli, Cristian, Zanesi, Nicola, Garzon, Ramiro, Aqeilan, Rami I., Alder, Hansjuerg, Volinia, Stefano, Rassenti, Laura, Liu, Xiuping, Liu, Chang-gong, Kipps, Thomas J., Negrini, Massimo, Croce, Carlo M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278188/
https://ncbi.nlm.nih.gov/pubmed/18362358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800121105
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