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MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin

It has been reported that persistent or excessive autophagy promotes cancer cell death during chemotherapy, either by enhancing the induction of apoptosis or mediating autophagic cell death. Here, we show that miR-15a and miR-16 are potent inducers of autophagy. Rictor, a component of mTORC2 complex...

詳細記述

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書誌詳細
出版年:Cancer Biol Ther
主要な著者: Huang, Nunu, Wu, Jiangbin, Qiu, Wei, Lyu, Qing, He, Jie, Xie, Weidong, Xu, Naihan, Zhang, Yaou
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622988/
https://ncbi.nlm.nih.gov/pubmed/25945419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040963
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