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MiR-15a and miR-16 induce autophagy and enhance chemosensitivity of Camptothecin
It has been reported that persistent or excessive autophagy promotes cancer cell death during chemotherapy, either by enhancing the induction of apoptosis or mediating autophagic cell death. Here, we show that miR-15a and miR-16 are potent inducers of autophagy. Rictor, a component of mTORC2 complex...
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| Vydáno v: | Cancer Biol Ther |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622988/ https://ncbi.nlm.nih.gov/pubmed/25945419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1040963 |
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