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Role of miR-15/16 in CLL
B-cell chronic lymphocytic leukemia (CLL) is the most common adult leukemia. The most common chromosomal abnormalities detectable by cytogenetics include deletion at 13q (55%), 11q (18%), trisomy 12 (12–16%) and 17p (8%). In 2002, we discovered that a microRNA cluster miR-15a/miR-16-1 (miR-15/16) is...
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| Publicat a: | Cell Death Differ |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262785/ https://ncbi.nlm.nih.gov/pubmed/24971479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.87 |
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