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Structural studies reveal thalidomide's mechanism of action and clinical effects: crystal clear or clearly complexed?
Another piece of the thalidomide puzzle is unraveled through structural studies of thalidomide and its derivatives bound to its protein target cereblon. Two recent studies published in Nature (Fischer et al.) and Nature Structural & Molecular Biology (Chamberlain et al.) have shed light on the d...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622570/ https://ncbi.nlm.nih.gov/pubmed/25692618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.972828 |
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