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Mechanism of action and NAD(+)-binding mode revealed by the crystal structure of l-histidinol dehydrogenase
The histidine biosynthetic pathway is an ancient one found in bacteria, archaebacteria, fungi, and plants that converts 5-phosphoribosyl 1-pyrophosphate to l-histidine in 10 enzymatic reactions. This pathway provided a paradigm for the operon, transcriptional regulation of gene expression, and feedb...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122284/ https://ncbi.nlm.nih.gov/pubmed/11842181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022476199 |
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