Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms

Relative of Early Flowing 6 (REF6) is a DNA-sequence-specific H3K27me3/2 demethylase that contains four zinc finger (ZnF) domains and targets several thousand genes in Arabidopsis thaliana. The ZnF domains are essential for binding target genes, but the structural basis remains unclear. Here, we det...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Discov
Main Authors: Tian, Zizi, Li, Xiaorong, Li, Min, Wu, Wei, Zhang, Manfeng, Tang, Chenjun, Li, Zhihui, Liu, Yunlong, Chen, Zhenhang, Yang, Meiting, Ma, Lulu, Caba, Cody, Tong, Yufeng, Lam, Hon-Ming, Dai, Shaodong, Chen, Zhongzhou
Formato: Artigo
Idioma:Inglês
Publicado: Springer Singapore 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7105484/
https://ncbi.nlm.nih.gov/pubmed/32257379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0150-6
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares