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Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
N(6)-Methylation of adenosine is the most ubiquitous and abundant modification of nucleoside in eukaryotic mRNA and long non-coding RNA. This modification plays an essential role in the regulation of mRNA translation and RNA metabolism. Recently, human AlkB homolog 5 (Alkbh5) and fat mass- and obesi...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002068/ https://ncbi.nlm.nih.gov/pubmed/24616105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546168 |
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