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Crystallization and preliminary X-ray diffraction of the RNA demethylase ALKBH5
N (6)-Methyladenosine (m6A) is a ubiquitous modification found in mammalian mRNA and long noncoding RNA. ALKBH5 is a member of the iron(II)- and 2-oxoglutarate-dependent AlkB oxygenase family and has been shown to catalyze the oxidative demethylation of N (6)-methyladenosine in RNA. The ALKBH5 pro...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
International Union of Crystallography
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818040/ https://ncbi.nlm.nih.gov/pubmed/24192356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113024858 |
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