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New mechanism of lenalidomide activity

Lenalidomide is an immunomodulatory agent (IMiD) that has activity in hematologic cancer (e.g., multiple myeloma). The immunomodulatory and apoptotic properties are readily apparent in therapy. However, the exact mechanism of action has been difficult to quantify until recently when it was shown tha...

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Detalhes bibliográficos
Main Authors: Keevan, Jacob, Figg, William D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119080/
https://ncbi.nlm.nih.gov/pubmed/24840055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29189
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