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Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display

Antibodies are indispensable tools in biochemical research and play an expanding role as therapeutics. While hybridoma technology is the dominant method for antibody production, phage display is an emerging technology. Here, we developed and employed a high-throughput pipeline that enables selection...

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Foilsithe in:Protein Sci
Main Authors: Huang, Haiming, Economopoulos, Nicolas O, Liu, Bernard A, Uetrecht, Andrea, Gu, Jun, Jarvik, Nick, Nadeem, Vincent, Pawson, Tony, Moffat, Jason, Miersch, Shane, Sidhu, Sachdev S
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley & Sons, Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622221/
https://ncbi.nlm.nih.gov/pubmed/26332758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2799
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