Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display

Antibodies are indispensable tools in biochemical research and play an expanding role as therapeutics. While hybridoma technology is the dominant method for antibody production, phage display is an emerging technology. Here, we developed and employed a high-throughput pipeline that enables selection...

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Dettagli Bibliografici
Pubblicato in:Protein Sci
Autori principali: Huang, Haiming, Economopoulos, Nicolas O, Liu, Bernard A, Uetrecht, Andrea, Gu, Jun, Jarvik, Nick, Nadeem, Vincent, Pawson, Tony, Moffat, Jason, Miersch, Shane, Sidhu, Sachdev S
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622221/
https://ncbi.nlm.nih.gov/pubmed/26332758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2799
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