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Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display

Antibodies are indispensable tools in biochemical research and play an expanding role as therapeutics. While hybridoma technology is the dominant method for antibody production, phage display is an emerging technology. Here, we developed and employed a high-throughput pipeline that enables selection...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Huang, Haiming, Economopoulos, Nicolas O, Liu, Bernard A, Uetrecht, Andrea, Gu, Jun, Jarvik, Nick, Nadeem, Vincent, Pawson, Tony, Moffat, Jason, Miersch, Shane, Sidhu, Sachdev S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622221/
https://ncbi.nlm.nih.gov/pubmed/26332758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2799
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