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Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display

Antibodies are indispensable tools in biochemical research and play an expanding role as therapeutics. While hybridoma technology is the dominant method for antibody production, phage display is an emerging technology. Here, we developed and employed a high-throughput pipeline that enables selection...

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Huang, Haiming, Economopoulos, Nicolas O, Liu, Bernard A, Uetrecht, Andrea, Gu, Jun, Jarvik, Nick, Nadeem, Vincent, Pawson, Tony, Moffat, Jason, Miersch, Shane, Sidhu, Sachdev S
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622221/
https://ncbi.nlm.nih.gov/pubmed/26332758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2799
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