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Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation
We investigated N-glycan processing of immunoglobulin G1 using the monoclonal antibody cetuximab (CxMab), which has a glycosite in the Fab domain in addition to the conserved Fc glycosylation, as a reporter. Three GlcNAc (Gn) terminating bi-antennary glycoforms of CxMab differing in core fucosylatio...
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| Gepubliceerd in: | MAbs |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622071/ https://ncbi.nlm.nih.gov/pubmed/26067753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1053683 |
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