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Expression and glycoengineering of functionally active heteromultimeric IgM in plants

IgM antibodies are an important player of the human’s innate defense mechanisms and increasingly have gained interest as therapeutics. Although the expression of IgM antibodies in mammalian cell culture is established, this approach remains costly and alternative methods have not been developed yet....

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Detalhes bibliográficos
Main Authors: Loos, Andreas, Gruber, Clemens, Altmann, Friedrich, Mehofer, Ulrich, Hensel, Frank, Grandits, Melanie, Oostenbrink, Chris, Stadlmayr, Gerhard, Furtmüller, Paul G., Steinkellner, Herta
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035941/
https://ncbi.nlm.nih.gov/pubmed/24706782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320544111
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