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Expression and glycoengineering of functionally active heteromultimeric IgM in plants

IgM antibodies are an important player of the human’s innate defense mechanisms and increasingly have gained interest as therapeutics. Although the expression of IgM antibodies in mammalian cell culture is established, this approach remains costly and alternative methods have not been developed yet....

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Bibliografische gegevens
Hoofdauteurs: Loos, Andreas, Gruber, Clemens, Altmann, Friedrich, Mehofer, Ulrich, Hensel, Frank, Grandits, Melanie, Oostenbrink, Chris, Stadlmayr, Gerhard, Furtmüller, Paul G., Steinkellner, Herta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035941/
https://ncbi.nlm.nih.gov/pubmed/24706782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320544111
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