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Expression and glycoengineering of functionally active heteromultimeric IgM in plants
IgM antibodies are an important player of the human’s innate defense mechanisms and increasingly have gained interest as therapeutics. Although the expression of IgM antibodies in mammalian cell culture is established, this approach remains costly and alternative methods have not been developed yet....
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035941/ https://ncbi.nlm.nih.gov/pubmed/24706782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320544111 |
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